Amiridin - stimulating neuromuscular transmission, anticholinesterase.


Apply to animals for stimulation of labor activity, increase of tone and physiological activity of the uterus after childbirth, with delay of digestion, endometritis, uterine subinvolution; for the treatment of paresis and paralysis, including which are accompanied by infectious diseases (plague of carnivorous and others), caused by traumas or other reasons; for the restoration of muscle tone after operations with the use of muscle relaxants, for the treatment of hypotension and atony of the digestive canal and bladder in animals; colic with co-mastases and coprostases; in neuritis (after taking off the pain syndrome).

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Amiridin
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Description

Description

Transparent liquid with a light yellow tint.

Compound

1 ml of the drug contains active ingredient:

ipidacrine (amiridine)- 10 mg,

water for injections 1 ml.

Pharmacological properties

Stimulates the neuromuscular transmission of impulses and conducts excitation along the nerves and smooth muscles, due to the effect on the potassium channels of the excitatory membrane and inhibition of the activity of cholinesterase, prevents hydrolytic decomposition of acetylcholine. It works like transzera, but weaker and less toxic. Strengthens the action of smooth muscle acetylcholine, adrenaline, serotonin, histamine and oxytocin. Raises the tonus and increases the muscle contraction of the stomach, intestine, uterus, bladder.

Application

Apply to animals for stimulation of labor activity, increase of tone and physiological activity of the uterus after childbirth, with delay of digestion, endometritis, uterine subinvolution; for the treatment of paresis and paralysis, including which are accompanied by infectious diseases (plague of carnivorous and others), caused by traumas or other reasons; for the restoration of muscle tone after operations with the use of muscle relaxants, for the treatment of hypotension and atony of the digestive canal and bladder in animals; colic with co-mastases and coprostases; in neuritis (after taking off the pain syndrome).

Dosage

The drug is injected to the dogs subcutaneously in a dose of 1 ml per 10 kg of body weight, for cats 0.1-0.2 ml per 1 kg of body weight 1-2 times a day for stimulation of labor, the injection is repeated 2-3 times at an hourly interval; At gynecological diseases (delay of litter, endometritis and subinvolution of the uterus), the drug is administered at intervals of 12 hours between administration; For the treatment of severe neuromuscular disorders (paresis and paralysis), the drug is administered 2 times a day.

The drug is injected to animals intramuscularly or subcutaneously in a dose of 0.2 ml per 10 kg of body weight twice with an interval of 2 hours in diseases of the intestine, with severe disorders of the functions of the digestive canal, the single dose can be increased to 0.4 ml per 10 kg of mass body.

The drug is injected to other animals intramuscularly or subcutaneously in a dose of 0.2-0.3 ml per 10 kg of body weight for the induction of childbirth, the injection is repeated 2-3 times with an hour interval in doses of 0.2-0.3 ml 10 kg of body weight at intervals of 12 hours between the introduction to recovery at the delay of the litter; at endometritis, subinvolyutsii uterus, ovarian bone drug is administered 1 time per day for 5-7 days, with more effective use of the drug in combination with antibacterial drugs.

Contraindication

The last trimester of pregnancy in females, epileptic seizures, diarrhea, vomiting, exacerbation of urolithiasis, circulatory disease, acute course of infectious diseases.

Warning

The drug is not compatible with iodine preparations, salts of heavy metals, alkali, oxidizing agents and salts of sulfanilamide preparations.

In case of overdose gipersalivation, bradycardia. In such cases, reduce the dose or discontinue the drug. Hypersalivation and bradycardia are lowered by cholinolytics (atropine and others).

Form of release

Glass bottles of 10 ml, closed with a rubber crust under an aluminum rim, enclosed in a cardboard box of 5 pieces

Storage

A dry, dark, inaccessible place for children at a temperature from 5 ° C to 25 ° C.

Expiration date – 2 роки.

After puncture, keep at a temperature from 4 ° C to 10 ° C for no more than 3 days.

For applying in veterinary medicine!

Product Details
Amiridin

Data sheet

Weight
100

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