Mildronate hard capsules 250 mg, 40 pcs.

Under conditions of increased load, MILDRONAT® restores the balance between the delivery and demand of cells for oxygen, eliminates the accumulation of toxic metabolic products in cells, protecting them from damage; also has a tonic effect. As a result of its use, the body acquires the ability to withstand the load and quickly restore energy reserves.

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In complex therapy in the following cases:

  • diseases of the heart and vascular system: stable angina pectoris, chronic heart failure (NYHA I-III functional class), cardiomyopathy, functional disorders of the heart and vascular system;
  • acute and chronic ischemic cerebrovascular accidents
  • reduced performance, physical and psycho-emotional overstrain;
  • during the recovery period after cerebrovascular disorders, head injuries and encephalitis.

Application features

When using the drug, patients with impaired liver and / or kidney function of mild or moderate severity in history should be careful (it is necessary to monitor liver and / or kidney function).

Many years of experience in the treatment of acute myocardial infarction and unstable angina in cardiology departments shows that meldonium is not a first-line drug in acute coronary syndrome.

Due to the possible development of an exciting effect, the drug is recommended to be used in the morning.

The ability to influence the reaction rate when driving vehicles or working with mechanisms

Studies to assess the impact on the ability to drive vehicles and maintain mechanisms have not been conducted.

Use during pregnancy or lactation

Pregnancy.  Animal studies are insufficient to assess the effect of meldonium on pregnancy, embryo/fetal development, childbirth and postpartum development. The potential risk to humans is unknown, so meldonium is contraindicated during pregnancy.

Lactation. Available animal data indicate the penetration of meldonium into mother's milk. It is not known whether meldonium passes into human breast milk. A risk to newborns/infants cannot be excluded, therefore meldonium is contraindicated during breastfeeding.

Dosage and administration

Take orally before or after meals. The capsule is swallowed with water. Due to the possible stimulating effect, the drug is recommended to be used in the morning.


Diseases of the heart and circulatory system, disorders of cerebral circulation

The daily dose is 500-1000 mg, you can use the entire dose at one time or distribute it into 2 doses. The maximum daily dose is 1000 mg.

With reduced performance, overstrain, during the recovery period

The daily dose is 500 mg. The maximum daily dose is 500 mg.

The duration of the course of treatment is 4-6 weeks. The course of treatment can be repeated 2-3 times a year.

Elderly patients

For elderly patients with impaired liver and / or kidney function, it may be necessary to reduce the dose of meldonium.

Patients with impaired renal function

Since the drug is excreted from the body by the kidneys, patients with mild to moderate renal impairment should use a lower dose of meldonium.

Patients with impaired liver function

Patients with mild to moderate hepatic impairment should use a lower dose of meldonium.


There are no data on the safety and efficacy of meldonium in children under 18 years of age, so the use of meldonium in this category of patients is contraindicated.


No cases of meldonium overdose have been reported. The drug has low toxicity and does not cause threatening side effects.

With low blood pressure, headaches, dizziness, tachycardia, and general weakness are possible. Treatment is symptomatic.

In case of severe overdose, it is necessary to monitor the functions of the liver and kidneys.

Hemodialysis is not significant in case of an overdose of meldonium due to its pronounced binding to blood proteins.

Best before date

4 years.

Do not use after the expiration date.

Storage conditions

Store at a temperature not exceeding 25 °C.

Store in original packaging to protect from moisture.

Keep out of the reach of children.


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